Determined to be brave, six-year-old Ramona Quimby has to deal with starting first grade, her mother's new job, and a teacher who does not understand how hard it is for Ramona to grow up.
Beatrice Quimby's biggest problem was her little sister, Ramona. Beatrice was very patient with Ramona, but eventually she got so exasperated that she decided she did not like Ramona at all.